Susan Johnson
Dr. Susan Johnson is a postdoctoral fellow in Dr. Streeck’s laboratory. Dr. Johnson was awarded a Melbourne Research Scholarship in 2005 for her doctoral training in Andrew Lew’s laboratory at the prestigious Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia. After completing her thesis in 2008 she was awarded a highly competitive NHMRC biomedical overseas early career fellowship to study T cell specificities in Daniel Pinschewer’s laboratory at the WHO Collaborating Centre for Neonatal Immunology and Vaccinology and the University of Geneva, Switzerland.
Dr. Johnson’s passion lies in studying the protective capacity of T cells and how these cells can be exploited for vaccine purposes. Her dissertation discovered that CD40L expression on dendritic cells is important for priming CD8 T cells in the absence of CD4 T cells in viral infection and her postdoctoral fellowship identified that individual T cell specificities control chronic infection. In 2013 she joined Dr. Streeck’s laboratory where she will study protective T cells in the context of HIV vaccine immunology.
As well as her research, Dr. Johnson also involves herself in science communication. She previously taught at the Gene Technology Access Centre, participated as a finalist in the Famelab scientific communication competition and now volunteers at the Genome exhibition at the Smithsonian Museum of Natural History.
Honors and Awards
2013 Young Investigator Award to speak at the American Association of Immunology Annual Conference
2011 ENII scholarship to speak at the 6th ENII Immunology Summer School
2010 Poster prize: Joint Annual Congress of the Swiss Society of Allergology and Immunology and the Swiss Society for Infectious Diseases
2009 Invitation and scholarship to the RIKEN Center for Allergy and Immunology International Summer Program
2009 NHMRC Biomedical overseas postdoctoral training fellowship (4 years funding)
2007 Aegean Conferences Award
2007 Melbourne Abroad Scholarship
2006 JDRF Postgraduate International Travel Award
2006 ASI Annual Conference Award
2005 Melbourne Research Scholarship to undertake PhD at University of Melbourne (3 years funding)
Publications
The Alarmin Interleukin-33 Drives Protective Antiviral CD8+ T Cell Responses.
Bonilla WV, Fröhlich A, Senn K, Kallert S, Fernandez M, Johnson S, Kreutzfeldt M, Hegazy AN, Schrick C, Fallon PG, Klemenz R, Nakae S, Adler H, Merkler D, Löhning M, Pinschewer DD.
Science. 2012 Feb 24;335(6071):984-9
The viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression
Bergthaler A, Flatz L, Hegazy AN, Johnson S, Horvath E, Löhning M and Pinschewer DD
PNAS 2010 Dec 14;107(50):21641-6
Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity.
Flatz L, Hegazy AN, Bergthaler A, Verschoor A, Claus C, Fernandez M, Gattinoni L, Johnson S, Kreppel F, Kochanek S, Broek M, Radbruch A, Lévy F, Lambert PH, Siegrist CA, Restifo NP, Löhning M, Ochsenbein AF, Nabel GJ, Pinschewer DD.
Nature Medicine 2010 Mar;16(3):339-45.
Selected TLR ligands and viruses promote helper-independent CTL priming by upregulating CD40L (CD154) on dendritic cells
Johnson S, Zhan Y, Mount A, Bedoui S, Brady JL, Carrington EM, Belz GT, Sutherland RM, Heath WR and Lew AM
Immunity 2009 February; 30; 218-227
Johnson S, Bourges D, Wijburg O, Strugnell RA, Lew AM.
Milk IgA responses are augmented by antigen delivery to the mucosal addressin cellular adhesion molecule-1
Vaccine 2006 July; 24(27-28);5552-5558
McKenzie BS, Corbett AJ, Johnson S, Brady JL, Pleasance J, Kramer DR, Boyle JS, Jackson DC, Strugnell RA, Lew AM.
Bypassing luminal barriers, delivery to a gut addressin by parenteral targeting elicits local IgA responses.
International Immunology 2004 Nov;16 (11);1613-22